{"id":777,"date":"2014-10-27T00:09:43","date_gmt":"2014-10-26T21:09:43","guid":{"rendered":"http:\/\/e-endocrinology.gr\/?page_id=777"},"modified":"2015-02-18T01:30:59","modified_gmt":"2015-02-17T22:30:59","slug":"10-16-1-%cf%85%cf%80%ce%bf%ce%ba%ce%bb%ce%b9%ce%bd%ce%b9%ce%ba%cf%8c%cf%82-%cf%85%cf%80%ce%b5%cf%81%ce%b8%cf%85%cf%81%ce%bf%ce%b5%ce%b9%ce%b4%ce%b9%cf%83%ce%bc%cf%8c%cf%82-%ce%b8%cf%85%cf%81%ce%b5","status":"publish","type":"page","link":"https:\/\/e-endocrinology.gr\/?page_id=777","title":{"rendered":"10.16 \u03a5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 &#8211; \u0398\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7"},"content":{"rendered":"<p style=\"text-align: right;\"><div class=\"printfriendly pf-button  pf-alignright\">\n                    <a href=\"https:\/\/e-endocrinology.gr\/?page_id=777&#038;pfstyle=wp\" rel=\"nofollow\" onclick=\"\" title=\"Printer Friendly, PDF & Email\">\n                    <img decoding=\"async\" class=\"pf-button-img\" src=\"https:\/\/cdn.printfriendly.com\/buttons\/printfriendly-pdf-button-nobg.png\" alt=\"Print Friendly, PDF & Email\" style=\"width: 112px;height: 24px;\"  \/>\n                    <\/a>\n                <\/div><\/p>\n<p><br class=\"none\" \/><\/p>\n<p style=\"text-align: right;\"><em>\u039d\u03b9\u03ba\u03cc\u03bb\u03b1\u03bf\u03c2 \u03a0\u03bf\u03bd\u03c4\u03b9\u03ba\u03af\u03b4\u03b7\u03c2, \u039c\u03b1\u03c1\u03af\u03b1 \u039a\u03b1\u03c1\u03b1\u03bc\u03c0\u03b1\u03c4\u03ac\u03ba\u03b7, \u03a3\u03c0\u03c5\u03c1\u03af\u03b4\u03c9\u03bd \u039a\u03b1\u03c1\u03c1\u03ac\u03c2<br \/>\n<\/em>K\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u0395\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 &#8211; \u03a3\u03b1\u03ba\u03c7\u03b1\u03c1\u03ce\u03b4\u03b7 \u0394\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7 \u03ba\u03b1\u03b9 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\u03c0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03ae \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc) \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2 (\u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c5\u03c0\u03bf\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u2013\u03a5\u03a5\u0398) \u03ae \u03c4\u03b7\u03c2 \u03c0\u03b5\u03c1\u03af\u03c3\u03c3\u03b5\u03b9\u03b1\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd (\u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7-\u03a5\u03a0\u0398).<\/p>\n<p style=\"text-align: justify;\">\u0397 \u03a5\u0398\u0394 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03b5\u03cd\u03c1\u03b5\u03c3\u03b7 \u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u03c4\u03b9\u03bc\u03ae\u03c2 TSH, \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03ae \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b1 \u03ba\u03b1\u03b9 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd Free T4 (FT4) \u03ba\u03b1\u03b9 Free T3 (FT3) (1, 2). \u0397 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03ac \u03bc\u03b1\u03c2 \u03bd\u03b1 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03bf\u03c5\u03bc\u03b5 \u03b4\u03b9\u03b1\u03c1\u03ba\u03ce\u03c2 \u03c0\u03b9\u03bf \u03ae\u03c0\u03b9\u03b5\u03c2 \u03b4\u03b9\u03b1\u03b2\u03b1\u03b8\u03bc\u03af\u03c3\u03b5\u03b9\u03c2 \u03c4\u03b7\u03c2 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\u03c3\u03b7\u03bc\u03b5\u03af\u03c9\u03bd &#8211; \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b5\u03bd\u03b4\u03b5\u03b9\u03ba\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03ac\u03c0\u03bf\u03b9\u03b1\u03c2 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03c3\u03b9\u03bc\u03b7\u03c2 \u03c0\u03ac\u03b8\u03b7\u03c3\u03b7\u03c2.<\/p>\n<p style=\"text-align: justify;\">\u039f\u03b9 \u03cc\u03c1\u03bf\u03b9 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03b1\u03c5\u03c4\u03cc\u03c3\u03b7\u03bc\u03bf\u03b9 \u03b1\u03bb\u03bb\u03ac \u03bf \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03bf\u03c2 \u03b5\u03bc\u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 \u03c4\u03bf\u03bd \u03c0\u03c1\u03ce\u03c4\u03bf. \u03a3\u03c4\u03bf\u03bd 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\u03b5\u03ba\u03ba\u03c1\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bd\u03bf\u03bc\u03cc\u03c4\u03bf\u03c0\u03bf \u03ae \u03ad\u03ba\u03c4\u03bf\u03c0\u03bf \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03b9\u03c3\u03c4\u03cc \u03ae \u03b5\u03ba\u03bb\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2\u00a0 \u03c0\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03bf\u03cd\u03bd \u03c3\u03b5 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae \u03c4\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b5\u03b3\u03c7\u03cd\u03bc\u03b1\u03c4\u03cc\u03c2 \u03c4\u03bf\u03c5 ( \u03c0\u03c7 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03af\u03c4\u03b9\u03b4\u03b5\u03c2) \u03ae \u03bf\u03c6\u03b5\u03af\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c5\u03c0\u03b5\u03c1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03bb\u03ae\u03c8\u03b7 (\u03c3\u03ba\u03bf\u03c0\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03ae \u03b9\u03b1\u03c4\u03c1\u03bf\u03b3\u03b5\u03bd\u03ae) \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd. \u0393\u03b9\u03b1 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03bb\u03cc\u03b3\u03bf\u03c5\u03c2 \u03c3\u03c4\u03bf \u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf \u03b8\u03b1 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7 (\u03a5\u03a0\u0398). \u038c\u03c0\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03a5\u03a5\u0398, \u03b3\u03b9\u03b1 \u03ba\u03b1\u03b8\u03b1\u03c1\u03ac \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03bf\u03cd\u03c2 \u03bb\u03cc\u03b3\u03bf\u03c5\u03c2 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b4\u03b9\u03b1\u03b2\u03ac\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03a5\u03a0\u0398, \u03c3\u03b5 \u03ae\u03c0\u03b9\u03b1 \u03a5\u03a0\u0398 \u03cc\u03c4\u03b1\u03bd \u03b7 TSH \u03b5\u03af\u03bd\u03b1\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03bc\u03b5\u03bd \u03b1\u03bb\u03bb\u03ac \u03bc\u03b5\u03c4\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 (0,1-0,4 mU\/L) \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03b9\u03bf \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03bc\u03bf\u03c1\u03c6\u03ae, \u03cc\u03c0\u03bf\u03c5 \u03b7 TSH \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03cc\u03c1\u03b9\u03c3\u03c4\u03b7 (&lt; 0,1 mU\/L) \u03ae \u03ba\u03b1\u03b9 \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 (3). \u03a3\u03c4\u03b7\u03bd \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03c9\u03bd (\u2265 75%) \u03b7 \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03ae\u03c0\u03b9\u03b1, \u03b5\u03bd\u03ce \u03c0\u03b9\u03bf \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03ba\u03b5\u03af\u03bd\u03b7 \u03c4\u03b7\u03c2 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae\u03c2 \u03a5\u03a0\u0398 (1,2).<\/p>\n<h4 style=\"text-align: justify;\"><b>1. \u0391\u03b9\u03c4\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1<\/b><\/h4>\n<p style=\"text-align: justify;\">\u03a3\u03b5 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03bf\u03b9 \u03ba\u03cd\u03c1\u03b9\u03b5\u03c2 \u03b1\u03b9\u03c4\u03af\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03a5\u03a0\u0398-\u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b5\u03c2 \u03bc\u03b5 \u03b5\u03ba\u03b5\u03af\u03bd\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf\u03c5 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd (<b>\u03a0\u03af\u03bd\u03b1\u03ba\u03b1\u03c2 1<\/b>). \u0393\u03b9\u03b1 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03bb\u03cc\u03b3\u03bf\u03c5\u03c2 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03a5\u03a0\u0398, \u03b7 \u03b4\u03b9\u03ac\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b3\u03af\u03bd\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03bf \u03c4\u03c1\u03cc\u03c0\u03bf \u03b5\u03ac\u03bd \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03b7 \u03a5\u03a0\u0398 \u03b5\u03af\u03bd\u03b1\u03b9 <b>\u03b5\u03be\u03c9\u03b3\u03b5\u03bd\u03ae\u03c2<\/b> \u03b1\u03c0\u03cc \u03c5\u03c0\u03b5\u03c1\u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 LT4 \u03ba\u03b1\u03b9 LT3, \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03c4\u03b7\u03bd \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c9\u03c2 \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03ae \u03c9\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u03ae <b>\u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae\u03c2.<\/b><\/p>\n<p style=\"text-align: justify;\"><b>\u03a0\u03af\u03bd\u03b1\u03ba\u03b1\u03c2 1<\/b>. \u0391\u03af\u03c4\u03b9\u03b1 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7\u03c2 [\u03bc\u03b5\u03c4\u03b1\u03c6\u03c1\u03b1\u03c3\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc Ross DS (10)].<\/p>\n<table style=\"width: 100%;\" border=\"0\" cellspacing=\"3\" cellpadding=\"3\" align=\"left\">\n<tbody>\n<tr style=\"background-color: #385a72;\">\n<td valign=\"top\"><b><span style=\"color: #ffffff;\">\u0391\u03af\u03c4\u03b9\u03b1<\/span> <\/b><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\"><b>\u0395\u03be\u03c9\u03b3\u03b5\u03bd\u03ae\u03c2 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7<\/b><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u03a5\u03c0\u03b5\u03c1\u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 LT4 \u03ae\/ \u03ba\u03b1\u03b9 LT3 \u03c3\u03b5 \u03c5\u03c0\u03bf\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u03a5\u03c0\u03b5\u03c1\u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 LT4 \u03ae\/ \u03ba\u03b1\u03b9 LT3 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03c5\u03c0\u03cc \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\"><b>\u0395\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae\u03c2 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7<\/b><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u03a4\u03bf\u03be\u03b9\u03ba\u03cc \u03b1\u03b4\u03ad\u03bd\u03c9\u03bc\u03b1, \u03c4\u03bf\u03be\u03b9\u03ba\u03ae \u03c0\u03bf\u03bb\u03c5\u03bf\u03b6\u03ce\u03b4\u03b7\u03c2 \u03b2\u03c1\u03bf\u03b3\u03c7\u03bf\u03ba\u03ae\u03bb\u03b7<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u039d\u03cc\u03c3\u03bf\u03c2 Graves\u2019 \u03c3\u03b5 \u03cd\u03c6\u03b5\u03c3\u03b7 \u03ae \u03c3\u03b5 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03c6\u03ac\u03c3\u03b7 \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae\u03c2<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u03a5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5\u03c4\u03ac \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7 (\u03b5\u03b3\u03c7\u03b5\u03af\u03c1\u03b7\u03c3\u03b7, RAI, \u03b1\u03bd\u03c4\u03b9\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae).<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\"><b>\u039a\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 <\/b><b>TSH<\/b><b> \u03c7\u03c9\u03c1\u03af\u03c2 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7 <\/b><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u039a\u03b5\u03bd\u03c4\u03c1\u03b9\u03ba\u03cc\u03c2 \u03c5\u03c0\u03bf\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u03a3\u03bf\u03b2\u03b1\u03c1\u03ae \u03bc\u03b7 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03bd\u03cc\u03c3\u03b7\u03c3\u03b7<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u039b\u03ae\u03c8\u03b7 \u03ba\u03bf\u03c1\u03c4\u03b9\u03ba\u03bf\u03c3\u03c4\u03b5\u03c1\u03bf\u03b5\u03b9\u03b4\u03ce\u03bd \u03ae \u03bd\u03c4\u03bf\u03c0\u03b1\u03bc\u03b9\u03bd\u03b5\u03c1\u03b3\u03b9\u03ba\u03ce\u03bd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u039c\u03b5\u03c4\u03ac \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03bd\u03b7\u03c8\u03b7 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03b8\u03b1\u03bb\u03b1\u03bc\u03bf-\u03c5\u03c0\u03bf\u03c6\u03c5\u03c3\u03b9\u03b1\u03ba\u03bf\u03cd-\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd \u03ac\u03be\u03bf\u03bd\u03b1<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u0394\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c7\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b3\u03bf\u03bd\u03b1\u03b4\u03bf\u03c4\u03c1\u03bf\u03c0\u03af\u03bd\u03b7\u03c2<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\">\u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03bb\u03ac\u03b8\u03bf\u03c2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5 style=\"text-align: justify;\"><b>1.1. \u0395\u03be\u03c9\u03b3\u03b5\u03bd\u03ae\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2<\/b><\/h5>\n<p style=\"text-align: justify;\">\u0397 \u03c0\u03b9\u03bf \u03c3\u03c5\u03c7\u03bd\u03ae \u03b1\u03b9\u03c4\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03be\u03c9\u03b3\u03b5\u03bd\u03bf\u03cd\u03c2 \u03a5\u03a0\u0398 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c5\u03c0\u03b5\u03c1\u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c3\u03b5 \u03c5\u03c0\u03bf\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03ae \u03c3\u03c4\u03b7 \u03c3\u03ba\u03bf\u03c0\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 TSH \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03c9\u03bc\u03b1 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03ae (\u0394\u0398\u039a) (1,2,4).<\/p>\n<p style=\"text-align: justify;\">\u039a\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03c4\u03b7 \u03c0\u03b5\u03c1\u03af\u03bf\u03b4\u03bf \u03c4\u03b7\u03c2 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03c0\u03b9\u03bf \u03b5\u03c5\u03b1\u03af\u03c3\u03b8\u03b7\u03c4\u03c9\u03bd \u03bc\u03b5\u03b8\u03cc\u03b4\u03c9\u03bd \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd \u03c4\u03b7\u03c2 TSH, \u03b5\u03af\u03c7\u03b5 \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03ad\u03bd\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd (40-50%) \u03c0\u03bf\u03c5 \u03bb\u03ac\u03bc\u03b2\u03b1\u03bd\u03b1\u03bd LT4 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03b6\u03b5 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 \u03c4\u03b9\u03bc\u03ae TSH (5). \u03a4\u03b1 \u03c5\u03c8\u03b7\u03bb\u03ac \u03b1\u03c5\u03c4\u03ac \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03ac \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5\u03b9\u03c9\u03b8\u03b5\u03af \u03c4\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1, \u03ba\u03ac\u03c4\u03b9 \u03c0\u03bf\u03c5 \u03bf\u03c6\u03b5\u03af\u03bb\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03b2\u03b1\u03b8\u03bc\u03cc \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03b3\u03bd\u03ce\u03c1\u03b9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03ce\u03bd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03c9\u03bd \u03c4\u03b7\u03c2 \u03c5\u03c0\u03b5\u03c1\u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03bc\u03b5 LT4. \u03a0\u03b1\u03c1\u03cc\u03bb\u03b1 \u03b1\u03c5\u03c4\u03ac, \u03cc\u03c0\u03c9\u03c2 \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03b9\u03b1\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7, \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc 19,8% \u03c0\u03bf\u03c5 \u03b5\u03bb\u03ac\u03bc\u03b2\u03b1\u03bd\u03b1\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03bc\u03b5 LT4 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03b6\u03b1\u03bd \u03c4\u03b9\u03bc\u03ad\u03c2 TSH &lt; 0,4 mU\/L (6). \u03a4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b1\u03c5\u03c4\u03cc \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b5 \u03b4\u03b9\u03c0\u03bb\u03ac\u03c3\u03b9\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c3\u03b5 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c3\u03b5 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03ac\u03bd\u03c9 \u03c9\u03bd 65 \u03b5\u03c4\u03ce\u03bd (7). \u0397 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03cc\u03bc\u03c9\u03c2 \u03c4\u03b7\u03c2 TSH \u03c3\u03b5 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03a5\u03a0\u0398 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c3\u03c4\u03cc\u03c7\u03bf \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u0394\u039a\u0398, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03b1\u03bd\u03ae\u03ba\u03bf\u03c5\u03bd \u03c3\u03b5 \u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 \u03c5\u03c8\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03ae \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c4\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03ac\u03bb\u03b9\u03c3\u03c4\u03b1 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03b3\u03c7\u03b5\u03af\u03c1\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 RAI (8,9). \u0388\u03c7\u03b5\u03b9 \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03c9\u03b8\u03b5\u03af \u03c4\u03cc\u03c3\u03bf \u03b1\u03c0\u03cc \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 in vitro, \u03cc\u03c4\u03b9 \u03b7 TSH \u03b4\u03b9\u03b5\u03b3\u03b5\u03af\u03c1\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03bc\u03cc \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03c9\u03bd \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b5\u03ba\u03c6\u03c1\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03c3\u03c6\u03b1\u03b9\u03c1\u03af\u03bd\u03b7\u03c2 (Tg). \u03a9\u03c2 \u03b5\u03ba \u03c4\u03bf\u03cd\u03c4\u03bf\u03c5, \u03b7 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 TSH, \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c9\u03c2 \u03b1\u03bd\u03b1\u03c3\u03c4\u03ad\u03bb\u03bb\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c5\u03c0\u03bf\u03bb\u03bb\u03b5\u03b9\u03bc\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03cd \u03bd\u03b5\u03bf\u03c0\u03bb\u03b1\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03cd \u03b9\u03c3\u03c4\u03bf\u03cd \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ce\u03bd (8,9). \u03a4\u03ad\u03bb\u03bf\u03c2, \u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c0\u03bf\u03bb\u03c5\u03bf\u03b6\u03ce\u03b4\u03b7 \u03bc\u03b7 \u03c4\u03bf\u03be\u03b9\u03ba\u03ae \u03b2\u03c1\u03bf\u03b3\u03c7\u03bf\u03ba\u03ae\u03bb\u03b7 \u03ae \u03b3\u03b5\u03bd\u03b9\u03ba\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c5\u03c4\u03bf\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03b9\u03c1\u03c1\u03b5\u03c0\u03b5\u03af\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b7 \u03a5\u03a0\u0398 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 LT4 (10).<\/p>\n<h5 style=\"text-align: justify;\"><b>1.2. \u0395\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2<\/b><\/h5>\n<p style=\"text-align: justify;\">\u039f \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae\u03c2 \u03a5\u03a0\u0398, \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03c5\u03c0\u03b5\u03c1\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c3\u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf \u03c4\u03bf\u03c5 \u03b1\u03c5\u03c4\u03cc\u03bd\u03bf\u03bc\u03bf\u03c5 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03bf\u03cd (\u03c4\u03bf\u03be\u03b9\u03ba\u03bf\u03cd) \u03b1\u03b4\u03b5\u03bd\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 (\u03a4\u0391), \u03c4\u03b7\u03c2 \u03c4\u03bf\u03be\u03b9\u03ba\u03ae\u03c2 \u03c0\u03bf\u03bb\u03c5\u03bf\u03b6\u03ce\u03b4\u03bf\u03c5\u03c2 \u03b2\u03c1\u03bf\u03b3\u03c7\u03bf\u03ba\u03ae\u03bb\u03b7\u03c2 (\u03a4\u03a0\u039f\u0392), \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 Graves\u2019, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae\u03c2 \u03c4\u03bf\u03c5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03cd \u03c0\u03b1\u03c1\u03b5\u03b3\u03c7\u03cd\u03bc\u03b1\u03c4\u03bf\u03c2 \u03bb\u03cc\u03b3\u03c9 \u03bb\u03b5\u03bc\u03c6\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae\u03c2 (\u03b1\u03bd\u03ce\u03b4\u03c5\u03bd\u03b7\u03c2) \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c5\u03c0\u03bf\u03be\u03b5\u03af\u03b1\u03c2 (\u03ba\u03bf\u03ba\u03ba\u03b9\u03c9\u03bc\u03b1\u03c4\u03ce\u03b4\u03bf\u03c5\u03c2) \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 (1,2,4,10-13). \u0397 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03a5\u03a0\u0398 \u03c0\u03bf\u03b9\u03ba\u03af\u03bb\u03b5\u03b9 \u03c3\u03c4\u03b9\u03c2 \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b1\u03c0\u03cc 0,7-9,0%, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03b9\u03b1\u03ba\u03ac \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac, \u03c4\u03b7\u03bd \u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03b9\u03c9\u03b4\u03af\u03bf\u03c5, \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1, \u03c4\u03b1 \u03cc\u03c1\u03b9\u03b1 \u03c4\u03b7\u03c2 TSH \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bc\u03b5\u03b8\u03bf\u03b4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd \u03c4\u03b7\u03c2 (1,2,4,13). \u03a3\u03b5 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03bc\u03ac\u03bb\u03b9\u03c3\u03c4\u03b1 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03ac\u03bd\u03c9 \u03c4\u03c9\u03bd 55 \u03b5\u03c4\u03ce\u03bd, \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc 57% \u03cc\u03c3\u03c9\u03bd \u03b5\u03af\u03c7\u03b1\u03bd \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b1\u03c5\u03c4\u03bf\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7\u03c2 \u03c3\u03b5 \u03ad\u03b4\u03b1\u03c6\u03bf\u03c2 \u03bf\u03b6\u03ce\u03b4\u03bf\u03c5\u03c2 \u03b2\u03c1\u03bf\u03b3\u03c7\u03bf\u03ba\u03ae\u03bb\u03b7\u03c2, \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b5 \u03a5\u03a0\u0398, \u03b5\u03bd\u03ce \u03c4\u03bf \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03a5\u03a0\u0398 \u03c0\u03bf\u03c5 \u03bf\u03c6\u03b5\u03af\u03bb\u03bf\u03bd\u03c4\u03b1\u03bd \u03c3\u03b5 \u03bd\u03cc\u03c3\u03bf Graves\u2019 \u03ae\u03c4\u03b1\u03bd \u03bc\u03cc\u03bb\u03b9\u03c2 6% (14). \u0397 \u03bd\u03cc\u03c3\u03bf\u03c2 Graves\u2019 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03b1\u03b9\u03c4\u03af\u03b1 \u03a5\u03a0\u0398, \u03c0\u03bf\u03c5 \u03b1\u03c0\u03b1\u03bd\u03c4\u03ac\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03bd\u03b5\u03ce\u03c4\u03b5\u03c1\u03b1 \u03ae \u03bc\u03ad\u03c3\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 \u03bc\u03b5 \u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03b9\u03c9\u03b4\u03af\u03bf\u03c5 (13), \u03b5\u03bd\u03ce \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1 \u03b7 \u03a4\u03a0\u039f\u0392 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03a4\u0391 \u03b1\u03bd\u03b5\u03c5\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 \u03bc\u03b5 \u03b9\u03c9\u03b4\u03b9\u03bf\u03c0\u03b5\u03bd\u03af\u03b1 (1,2,13). \u0391\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03ae\u03c0\u03b9\u03b1 \u03bd\u03cc\u03c3\u03bf Graves\u2019 (15) \u03ae \u03b5\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03b9\u03ba\u03ae \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 (16) \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03bd \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b3\u03b9\u03b1 \u03bc\u03b1\u03ba\u03c1\u03cc \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03b4\u03b9\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 TSH. \u03a3\u03b5 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae \u03b4\u03b5 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7, \u03ad\u03bd\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc 20% \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03b5\u03af\u03c7\u03b1\u03bd \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 TSH \u03bc\u03b5\u03c4\u03ac \u03c4\u03bf \u03c0\u03ad\u03c1\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7\u03c2 \u03b3\u03b9\u03b1 \u03bd\u03cc\u03c3\u03bf Graves\u2019 (\u03b1\u03bd\u03c4\u03b9\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1, \u03b5\u03b3\u03c7\u03b5\u03af\u03c1\u03b7\u03c3\u03b7 \u03ae RAI) \u03ba\u03b1\u03b9 \u03bc\u03ac\u03bb\u03b9\u03c3\u03c4\u03b1 \u03ae\u03c4\u03b1\u03bd \u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03c1\u03c1\u03b5\u03c0\u03b5\u03af\u03c2 \u03c3\u03b5 \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03af\u03c7\u03b5 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 TSH \u03bc\u03b5\u03c4\u03ac \u03c4\u03bf \u03c0\u03ad\u03c1\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7\u03c2 (17).<\/p>\n<h4 style=\"text-align: justify;\"><b>2. \u0394\u03b9\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/b><\/h4>\n<p style=\"text-align: justify;\">\u0397 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03a5\u03a0\u0398 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7\u03c2 \u03ae \u03b1\u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03cc\u03c1\u03b9\u03c3\u03c4\u03b7\u03c2 \u03c4\u03b9\u03bc\u03ae\u03c2 TSH. \u03a4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03b7\u03c2 FT4 \u03b1\u03bd\u03b5\u03c5\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03b1\u03bd\u03ce\u03c4\u03b5\u03c1\u03b1 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03cc\u03c1\u03b9\u03b1 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03b5\u03be\u03c9\u03b3\u03b5\u03bd\u03ae \u03a5\u03a0\u0398 (1,2,9), \u03b5\u03bd\u03ce \u03b5\u03ba\u03b5\u03af\u03bd\u03b1 \u03c4\u03b7\u03c2 FT3 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c5\u03b3\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b1 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b1 \u03c4\u03b7\u03c2 FT4 \u03ae \u03c3\u03c4\u03b1 \u03b1\u03bd\u03ce\u03c4\u03b5\u03c1\u03b1 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03cc\u03c1\u03b9\u03b1 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae \u03a5\u03a0\u0398 (1,2,13). \u03a3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03b5\u03bd\u03b4\u03bf- \u03ba\u03b1\u03b9 \u03b5\u03be\u03c9\u03b3\u03b5\u03bd\u03bf\u03cd\u03c2 \u03a5\u03a0\u0398 \u03b8\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03b7 \u03c0\u03c1\u03bf\u03c3\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03c3\u03b7\u03bc\u03b5\u03af\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7\u03c2, \u03c4\u03bf \u03b9\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03cc, \u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03c9\u03bd \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03c3\u03b5\u03c9\u03bd \u03ae \u03c3\u03c5\u03bd\u03bf\u03b4\u03ce\u03bd \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03c9\u03bd \u03bd\u03bf\u03c3\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd (\u03c0\u03c7 \u03b5\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03b9\u03ba\u03ae \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1) \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03c1\u03bf\u03c3\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 (13). \u0397 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03bf\u03b4\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u03c4\u03b7\u03c2 TSH, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b5\u03c0\u03b1\u03bd\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03cc\u03c1\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b5\u03af \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03ce\u03b4\u03c5\u03bd\u03b7 \u03ae \u03c3\u03b9\u03c9\u03c0\u03b7\u03bb\u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03af\u03c4\u03b9\u03b4\u03b1 \u03c4\u03b7\u03c2 \u03bb\u03bf\u03c7\u03b5\u03af\u03b1\u03c2 (1,2,18-20).<\/p>\n<p style=\"text-align: justify;\">\u039a\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 \u03c4\u03b9\u03bc\u03ae TSH \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03bc\u03b7 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03bd\u03cc\u03c3\u03b7\u03c3\u03b7, \u03bb\u03ae\u03c8\u03b7 \u03ba\u03bf\u03c1\u03c4\u03b9\u03ba\u03bf\u03c3\u03c4\u03b5\u03c1\u03bf\u03b5\u03b9\u03b4\u03ce\u03bd \u03ae \u03ba\u03b1\u03b9 \u03bd\u03c4\u03bf\u03c0\u03b1\u03bc\u03b9\u03bd\u03b5\u03c1\u03b3\u03b9\u03ba\u03ce\u03bd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd, \u03c5\u03c0\u03bf\u03c6\u03c5\u03c3\u03b9\u03b1\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c9\u03c2 \u03b5\u03ba \u03c4\u03bf\u03cd\u03c4\u03bf\u03c5 \u03bf\u03b9 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03b8\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd (1,2,18,20,21). \u0388\u03bd\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc 1-3% \u03b7\u03bb\u03b9\u03ba\u03b9\u03c9\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 60 \u03ad\u03c9\u03c2 &gt;80 \u03c7\u03c1\u03cc\u03bd\u03c9\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03b9 \u03c4\u03b9\u03bc\u03ae TSH &lt; 0,4 mU\/L \u03ba\u03b1\u03b9 \u03bc\u03b7 \u03b1\u03bd\u03c4\u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 TSH \u03c3\u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 TRH (1,2). \u03a4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03b1\u03c5\u03c4\u03ac \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03c4\u03b9\u03bc\u03ae FT3 \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b1\u03c0\u03bf\u03b4\u03af\u03b4\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c0\u03b5\u03c1\u03b9\u03c6\u03b5\u03c1\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c4\u03c1\u03bf\u03c0\u03ae \u03c4\u03b7\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd T4. \u039c\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c4\u03b9\u03bc\u03ce\u03bd \u03c4\u03b7\u03c2 TSH \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03c3\u03c5\u03c7\u03bd\u03ac \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c4\u03bf \u03c0\u03c1\u03ce\u03c4\u03bf \u03c4\u03c1\u03af\u03bc\u03b7\u03bd\u03bf \u03c4\u03b7\u03c2 \u03ba\u03cd\u03b7\u03c3\u03b7\u03c2, \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03c0\u03bf\u03c5 \u03b1\u03c0\u03bf\u03b4\u03af\u03b4\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c7\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b3\u03bf\u03bd\u03b1\u03b4\u03bf\u03c4\u03c1\u03bf\u03c0\u03af\u03bd\u03b7\u03c2 (1,2). \u039a\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03b7\u03c2 TSH \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf\u03c5 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 (\u03bd\u03cc\u03c3\u03bf\u03c2 Graves\u2019 \u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03af\u03c4\u03b9\u03b4\u03b1 Hashimoto \u2013 \u201chashitoxicocis\u201d) \u03ae \u03c0\u03bf\u03bb\u03c5\u03bf\u03b6\u03ce\u03b4\u03b7 \u03b2\u03c1\u03bf\u03b3\u03c7\u03bf\u03ba\u03ae\u03bb\u03b7. \u03a3\u03c4\u03b9\u03c2 \u03c0\u03b9\u03bf \u03c0\u03ac\u03bd\u03c9 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af \u03c0\u03c1\u03bf\u03bf\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03c4\u03b7\u03c2 FT3 \u03ae\/\u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 FT4 \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b7 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd. \u03a3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03a5\u03a0\u0398 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b5\u03c1\u03b9\u03ba\u03ce\u03c2 \u03ae \u03c0\u03bb\u03b7\u03bc\u03bc\u03b5\u03bb\u03ce\u03c2 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03b9\u03b6\u03cc\u03bc\u03b5\u03bd\u03bf\u03c5 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd, \u03bf \u03c5\u03c0\u03bf\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b1\u03c0\u03cc \u03b9\u03c9\u03b4\u03b9\u03bf\u03cd\u03c7\u03b1 \u03c3\u03ba\u03b5\u03c5\u03ac\u03c3\u03bc\u03b1\u03c4\u03b1, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03af\u03c4\u03b9\u03b4\u03b5\u03c2 (\u03c5\u03c0\u03bf\u03be\u03b5\u03af\u03b1, \u03c3\u03b9\u03c9\u03c0\u03b7\u03bb\u03ae \u03ae \u03c4\u03b7\u03c2 \u03bb\u03bf\u03c7\u03b5\u03af\u03b1\u03c2) (18,20,22). \u0395\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03ba\u03b1\u03b9 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03b1\u03af\u03c4\u03b9\u03b1 \u03a5\u03a0\u0398 \u03cc\u03c0\u03c9\u03c2 \u03b1\u03c5\u03c4\u03ae \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03b9\u03c9\u03b4\u03b9\u03bf\u03cd\u03c7\u03c9\u03bd \u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd, \u03b1\u03bc\u03b9\u03c9\u03b4\u03b1\u03c1\u03cc\u03bd\u03b7\u03c2, \u03b1\u03c0\u03cc \u03c4\u03c1\u03bf\u03c6\u03bf\u03b2\u03bb\u03b1\u03c3\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03cc\u03b3\u03ba\u03bf\u03c5\u03c2, \u03ae \u03b1\u03c0\u03cc \u03c3\u03ba\u03bf\u03c0\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 (factitia) \u03bb\u03ae\u03c8\u03b7 \u03c5\u03c0\u03b5\u03c1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ce\u03bd \u03c0\u03bf\u03c3\u03bf\u03c4\u03ae\u03c4\u03c9\u03bd \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd (19,23). \u03a3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b8\u03b7\u03ba\u03b1\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03bd \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03b7 24\u03c9\u03c1\u03b7 \u03c0\u03c1\u03cc\u03c3\u03bb\u03b7\u03c8\u03b7 RAI \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b1\u03bd\u03b5\u03c5\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf Graves\u2019 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c4\u03bf\u03be\u03b9\u03ba\u03ae \u03bf\u03b6\u03ce\u03b4\u03b7 (\u03a4\u0391), \u03ba\u03b1\u03b9 \u03c0\u03bf\u03bb\u03c5\u03bf\u03b6\u03ce\u03b4\u03b7 \u03b2\u03c1\u03bf\u03b3\u03c7\u03bf\u03ba\u03ae\u03bb\u03b7\u03c2 (\u03a4\u03a0\u039f\u0392), \u03b5\u03bd\u03ce \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 (&lt; 5%) \u03c3\u03c4\u03b7\u03bd \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03b9\u03ba\u03ae \u03c6\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c5\u03c0\u03bf\u03be\u03b5\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03ce\u03b4\u03c5\u03bd\u03b7\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03bb\u03bf\u03c7\u03b5\u03af\u03b1\u03c2 \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c0\u03bf\u03c3\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd (1,23). \u03a4\u03ad\u03bb\u03bf\u03c2, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03a5\u03a0\u0398 \u03b1\u03c0\u03cc \u03bd\u03cc\u03c3\u03bf Graves\u2019 \u03bf \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c4\u03c9\u03bd \u03b4\u03b9\u03b5\u03c1\u03b3\u03b5\u03c1\u03c4\u03b9\u03ba\u03ce\u03bd \u03b1\u03c5\u03c4\u03bf\u03b1\u03bd\u03c4\u03b9\u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c4\u03bf\u03c5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03ae (Thyroid Stimulating Immunoglobulins, TSI) \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03bd \u03bd\u03b1 \u03c0\u03c1\u03bf\u03b4\u03b9\u03ba\u03ac\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c3\u03b5 \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc, \u03b5\u03c6\u03cc\u03c3\u03bf\u03bd, \u03b1\u03bd\u03b5\u03c5\u03c1\u03b5\u03b8\u03bf\u03cd\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf\u03b9 \u03c4\u03af\u03c4\u03bb\u03bf\u03b9 (1,2).<\/p>\n<h4 style=\"text-align: justify;\"><b>3. \u0395\u03be\u03ad\u03bb\u03b9\u03be\u03b7 &#8211; \u03c6\u03c5\u03c3\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7\u03c2<\/b><\/h4>\n<p style=\"text-align: justify;\">\u039f\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03a5\u03a0\u0398 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03c3\u03c4\u03c1\u03ad\u03c8\u03b9\u03bc\u03b7 \u03ae \u03b5\u03bc\u03bc\u03ad\u03bd\u03bf\u03c5\u03c3\u03b1 \u03bd\u03cc\u03c3\u03bf \u03ae \u03b1\u03ba\u03cc\u03bc\u03b7 \u03bd\u03b1 \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03c3\u03bf\u03c5\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc. \u039f \u03c1\u03c5\u03b8\u03bc\u03cc\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03bf\u03c0\u03bf\u03af\u03bf \u03b7 \u03a5\u03a0\u0398 \u03b5\u03be\u03b5\u03bb\u03af\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ad\u03ba\u03b4\u03b7\u03bb\u03b7 \u03bd\u03cc\u03c3\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03b2\u03ad\u03b2\u03b1\u03b9\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b1\u03c1\u03c7\u03b9\u03ba\u03cc \u03b2\u03b1\u03b8\u03bc\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u03c4\u03b7\u03c2 TSH \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03b9\u03c4\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03bf\u03cd\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd.<\/p>\n<p style=\"text-align: justify;\">\u039f \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03c0\u03c1\u03bf\u03cc\u03b4\u03bf\u03c5 \u03c3\u03b5 \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03bf\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bd\u03cc\u03c3\u03bf Graves\u2019 \u03c0\u03b1\u03c1\u03ac \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03be\u03b9\u03ba\u03ae \u03bf\u03b6\u03ce\u03b4\u03b7 \u03ae \u03c0\u03bf\u03bb\u03c5\u03bf\u03b6\u03ce\u03b4\u03b7 \u03b2\u03c1\u03bf\u03b3\u03c7\u03bf\u03ba\u03ae\u03bb\u03b7 (2,24-26). \u03a3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03bc\u03ac\u03bb\u03b9\u03c3\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03a5\u03a0\u0398 \u03b1\u03c0\u03cc \u03a4\u0391 \u03ae \u03a4\u03a0\u039f\u0392 \u03b7 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03c3\u03c5\u03bd\u03b7\u03b8\u03ad\u03c3\u03c4\u03b5\u03c1\u03b1 \u03bc\u03b5\u03c4\u03ac \u03b5\u03c0\u03b1\u03c6\u03ae \u03bc\u03b5 \u03b9\u03c9\u03b4\u03b9\u03bf\u03cd\u03c7\u03b1 \u03c3\u03ba\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03bc\u03ad\u03c3\u03b1 \u03ae \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 \u03c0\u03b9\u03bf \u00ab\u03c3\u03bf\u03b2\u03b1\u03c1\u03ae\u00bb \u03a5\u03a0\u0398 (27,28). \u039c\u03b1\u03ba\u03c1\u03ac\u03c2 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 (1 &#8211; 4 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1) \u03c0\u03b1\u03c1\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c4\u03bf\u03c5 \u03a5\u03a0\u0398 \u03c3\u03b5 \u03ad\u03ba\u03b4\u03b7\u03bb\u03b7 \u03bd\u03cc\u03c3\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03b5\u03af \u03bc\u03b5 \u03ad\u03bd\u03b1\u03bd \u03b5\u03c4\u03ae\u03c3\u03b9\u03bf \u03c1\u03c5\u03b8\u03bc\u03cc \u03c0\u03bf\u03c5 \u03ba\u03c5\u03bc\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc 1-5% (29-33). \u03a3\u03b5 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03bb\u03ac\u03bc\u03b2\u03b1\u03bd\u03b5 33 \u03b7\u03bb\u03b9\u03ba\u03b9\u03c9\u03bc\u03ad\u03bd\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5 TSH &lt; 0,1 mU\/L, \u03c4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b1\u03bd\u03b5\u03cd\u03c1\u03b5\u03c3\u03b7\u03c2 \u03a0\u039f\u0392 \u03ae\u03c4\u03b1\u03bd \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c3\u03c5\u03bd\u03bf\u03bc\u03ae\u03bb\u03b9\u03ba\u03bf\u03c5\u03c2 \u03bc\u03ac\u03c1\u03c4\u03c5\u03c1\u03b5\u03c2 (68% \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 29%) (34). T\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03b4\u03b5 \u03b1\u03c5\u03c4\u03ac \u03bc\u03b5 \u03c4\u03bf\u03bd \u03a5\u03a0\u0398 \u03ae\u03c4\u03b1\u03bd \u03c0\u03b9\u03bf \u03b5\u03c0\u03b9\u03c1\u03c1\u03b5\u03c0\u03ae \u03c3\u03c4\u03b7\u03bd \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03ad\u03ba\u03b4\u03b7\u03bb\u03b7\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2 (2 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1): 30% \u03ad\u03b3\u03b9\u03bd\u03b1\u03bd \u03ad\u03ba\u03b4\u03b7\u03bb\u03b1 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03bf\u03af, 23% \u03c0\u03b1\u03c1\u03ad\u03bc\u03b5\u03b9\u03bd\u03b1\u03bd \u03bc\u03b5 \u03a5\u03a0\u0398 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 TSH, \u03b5\u03bd\u03ce 10% \u03b5\u03af\u03c7\u03b1\u03bd \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 TSH \u03c3\u03c4\u03b1 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03cc\u03c1\u03b9\u03b1 (35). \u039a\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd 12\u03bc\u03b7\u03bd\u03b7 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 66 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03ac\u03bd\u03c9 \u03c4\u03c9\u03bd 60 \u03c7\u03c1\u03cc\u03bd\u03c9\u03bd \u03bc\u03b5 \u03a5\u03a0\u0398, \u03b7 TSH \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf\u03c5\u03c2 38 \u03b1\u03c0\u03cc 50 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03c0\u03bb\u03b7\u03bd \u03cc\u03bc\u03c9\u03c2 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03c3\u03b9\u03bc\u03b7 \u03c4\u03b9\u03bc\u03ae TSH, \u03b5\u03bd\u03ce \u03c0\u03b1\u03c1\u03ad\u03bc\u03b5\u03b9\u03bd\u03b5 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c5\u03c0\u03cc\u03bb\u03bf\u03b9\u03c0\u03bf\u03c5\u03c2 14 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2 16 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ac \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03af\u03c7\u03b1\u03bd \u03b1\u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03cc\u03c1\u03b9\u03c3\u03c4\u03b7 \u03c4\u03b9\u03bc\u03ae TSH, \u03b5\u03bd\u03ce \u03bc\u03cc\u03bd\u03bf \u03ad\u03bd\u03b1\u03c2 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03bf\u03cd\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc (29). \u03a4\u03bf \u03bc\u03ae\u03bd\u03c5\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ae \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u00ab\u03ae\u03c0\u03b9\u03b1\u00bb \u03a5\u03a0\u0398 (1,2% \u03c4\u03bf \u03c7\u03c1\u03cc\u03bd\u03bf) \u03c0\u03b1\u03c1\u03ac \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b1\u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03cc\u03c1\u03b9\u03c3\u03c4\u03b7 \u03c4\u03b9\u03bc\u03ae TSH (29).<\/p>\n<p style=\"text-align: justify;\">\u0391\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03ba\u03b1\u03b9 \u03b4\u03cd\u03bf \u03b1\u03ba\u03cc\u03bc\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7\u03c2 \u03c3\u03b5 15 \u03ba\u03b1\u03b9 33 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b1 \u03ac\u03bd\u03c9 \u03c4\u03c9\u03bd 60 \u03c7\u03c1\u03cc\u03bd\u03c9\u03bd \u03bc\u03b5 \u00ab\u03c3\u03bf\u03b2\u03b1\u03c1\u03ae\u00bb \u03a5\u03a0\u0398 \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b3\u03b9\u03b1 4-12 \u03bc\u03ae\u03bd\u03b5\u03c2 (36) \u03ba\u03b1\u03b9 \u03bc\u03ad\u03c7\u03c1\u03b9 4 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 (30) \u03ba\u03b9 \u03cc\u03c0\u03bf\u03c5 \u03c4\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03ac \u03b1\u03bd\u03ac\u03bd\u03b7\u03c8\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03a5\u03a0\u0398 \u03ae\u03c4\u03b1\u03bd 45-70%., \u03b5\u03bd\u03ce, \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1 \u03c4\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03ac \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03c3\u03b5 \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc \u03ae\u03c4\u03b1\u03bd 0 (36) \u03ba\u03b1\u03b9 6% (30), \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b1. \u03a4\u03ad\u03bb\u03bf\u03c2, \u03c4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03a5\u03a0\u0398 \u03c3\u03b5 \u03ad\u03ba\u03b4\u03b7\u03bb\u03b7 \u03bd\u03cc\u03c3\u03bf \u03c3\u03b5 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b7\u03c2 \u03ae \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b3\u03b9\u03b1 \u03bc\u03b1\u03ba\u03c1\u03cc \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03b4\u03b9\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1 10 \u03c7\u03c1\u03cc\u03bd\u03c9\u03bd, \u03b1\u03bd\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03bd \u03c3\u03c4\u03bf 43% (5).<\/p>\n<p style=\"text-align: justify;\">\u0391\u03bd\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03bf \u03b2\u03b1\u03b8\u03bc\u03cc \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03c4\u03c9\u03bd \u03b1\u03c5\u03c4\u03cc\u03bd\u03bf\u03bc\u03c9\u03bd \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ce\u03bd \u03cc\u03b6\u03c9\u03bd \u03c3\u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf \u03c4\u03b7\u03c2 \u03bf\u03b6\u03ce\u03b4\u03bf\u03c5\u03c2 \u03ae \u03c0\u03bf\u03bb\u03c5\u03bf\u03b6\u03ce\u03b4\u03bf\u03c5\u03c2 \u03b2\u03c1\u03bf\u03b3\u03c7\u03bf\u03ba\u03ae\u03bb\u03b7\u03c2, \u03b4\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b1\u03c1\u03ba\u03b5\u03c4\u03ac \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c3\u03c4\u03b7 \u03b2\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1. \u03a9\u03c3\u03c4\u03cc\u03c3\u03bf \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03b9 \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc \u03ad\u03c7\u03b5\u03b9 \u03cc\u03b6\u03bf\u03c5\u03c2 \u03b4\u03b9\u03b1\u03bc\u03ad\u03c4\u03c1\u03bf\u03c5 \u03ac\u03bd\u03c9 \u03c4\u03c9\u03bd 3 \u03b5\u03ba\u03b1\u03c4\u03bf\u03c3\u03c4\u03ce\u03bd (1). \u03a3\u03b5 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae \u03b4\u03b5 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03bf \u00ab\u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03bf\u03c2\u00bb \u03cc\u03b3\u03ba\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b7 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd \u03c5\u03c0\u03bf\u03bb\u03bf\u03b3\u03af\u03c3\u03c4\u03b7\u03ba\u03b5 \u03c3\u03c4\u03b1 16 \u03ba\u03c5\u03b2\u03b9\u03ba\u03ac \u03b5\u03ba\u03b1\u03c4\u03bf\u03c3\u03c4\u03ac.<\/p>\n<p style=\"text-align: justify;\">\u03a3\u03c5\u03bd\u03bf\u03c8\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bc\u03b5 \u03bd\u03b1 \u03c0\u03bf\u03cd\u03bc\u03b5 \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03a5\u03a0\u0398 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af \u03bc\u03b1\u03ba\u03c1\u03cc\u03bd, \u03b9\u03b4\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b5\u03ba\u03b5\u03af\u03bd\u03bf\u03b9 \u03bc\u03b5 \u03c4\u03b9\u03bc\u03ae TSH&lt;0,1 mU\/L \u03ba\u03b1\u03b9 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03ac\u03bd\u03c9 \u03c4\u03c9\u03bd 60 \u03c7\u03c1\u03cc\u03bd\u03c9\u03bd \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c6\u03cc\u03b2\u03bf \u03c4\u03b7\u03c2 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7\u03c2 \u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc. \u0388\u03c7\u03b5\u03b9 \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03bc\u03ac\u03bb\u03b9\u03c3\u03c4\u03b1 \u03cc\u03c4\u03b9 \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03b9\u03c1\u03c1\u03b5\u03c0\u03ae \u03c3\u03b5 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae\u03c2 \u03bc\u03b1\u03c1\u03bc\u03b1\u03c1\u03c5\u03b3\u03ae\u03c2 \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03bc\u03ac\u03bb\u03b9\u03c3\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03c4\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 (34).<\/p>\n<h4 style=\"text-align: justify;\"><b>4. \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7\u03c2<\/b><\/h4>\n<p style=\"text-align: justify;\">\u039c\u03bf\u03bb\u03bf\u03bd\u03cc\u03c4\u03b9 \u03b7 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 \u03c4\u03b9\u03bc\u03ae \u03c4\u03b7\u03c2 TSH \u03cc\u03c0\u03c9\u03c2 \u03ae\u03b4\u03b7 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b8\u03b7\u03ba\u03b5, \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03a5\u03a0\u0398, \u03b7 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03c4\u03c9\u03bd \u03b5\u03bb\u03b5\u03cd\u03b8\u03b5\u03c1\u03c9\u03bd \u03ba\u03bb\u03b1\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03c4\u03c9\u03bd \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd, \u03c0\u03bf\u03c5 \u03b5\u03c5\u03b8\u03cd\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 TSH \u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03b5 \u03ac\u03bb\u03bb\u03bf\u03c5\u03c2 \u03b9\u03c3\u03c4\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b1 \u03b1\u03bd \u03ba\u03b1\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03ad\u03ba\u03b4\u03b7\u03bb\u03b7, \u03bc\u03b5 \u03b5\u03ba\u03b5\u03af\u03bd\u03b7\u03bd \u03c4\u03b7\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7\u03c2. \u0395\u03af\u03bd\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae \u03b7 \u03b5\u03c5\u03b8\u03cd\u03b3\u03c1\u03b1\u03bc\u03bc\u03b7 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03c4\u03b9\u03bc\u03ce\u03bd \u03c4\u03b7\u03c2 TSH \u03ba\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03b5\u03ba\u03b5\u03af\u03bd\u03c9\u03bd \u03c4\u03b7\u03c2 FT4. \u03a3\u03c4\u03b7 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03bf\u03b9 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03c4\u03b7\u03c2 TSH \u00ab\u03ba\u03b9\u03bd\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9\u00bb \u03c3\u03b5 \u03bb\u03bf\u03b3\u03b1\u03c1\u03b9\u03b8\u03bc\u03b9\u03ba\u03ae \u03ba\u03bb\u03af\u03bc\u03b1\u03ba\u03b1. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9\u03b9 \u03cc\u03c4\u03b9 \u03ba\u03b1\u03b9 \u03bc\u03b9\u03ba\u03c1\u03ad\u03c2 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2 \u03c4\u03c9\u03bd \u03c3\u03c5\u03b3\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03c3\u03b5\u03c9\u03bd \u03c4\u03c9\u03bd \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd, \u03c3\u03c4\u03bf \u03c6\u03ac\u03c3\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd \u03b5\u03cd\u03c1\u03bf\u03c5\u03c2 \u03c4\u03c9\u03bd \u03c4\u03b9\u03bc\u03ce\u03bd \u03c4\u03bf\u03c5\u03c2, \u03ad\u03c7\u03b5\u03b9 \u03c9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03b4\u03c5\u03c3\u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ae \u03c4\u03c9\u03bd \u03c4\u03b9\u03bc\u03ce\u03bd \u03c4\u03b7\u03c2 TSH (<b>\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 1<\/b>). \u0388\u03c4\u03c3\u03b9 \u03b7 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 \u03c4\u03b9\u03bc\u03ae \u03c4\u03b7\u03c2 TSH \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03ac\u03c4\u03bf\u03bc\u03bf \u03ba\u03ac\u03c0\u03bf\u03b9\u03b1 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03bd \u03bd\u03b1 \u03b1\u03c0\u03bf\u03c4\u03c5\u03c0\u03ce\u03bd\u03b5\u03b9 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ac \u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7 \u03c4\u03bf \u03ac\u03c4\u03bf\u03bc\u03bf.<\/p>\n<hr style=\"width: 100%; border-width: 1px; border-style: solid; border-color: #CCCCCC; color: #ffffff;\" noshade=\"noshade\" width=\"100%\" \/>\n<p style=\"text-align: justify;\"><b>\u00a0<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-781\" alt=\"10.16-figure1\" src=\"https:\/\/e-endocrinology.gr\/wp-content\/uploads\/2014\/10\/10.16-figure1.jpg\" width=\"650\" height=\"602\" srcset=\"https:\/\/e-endocrinology.gr\/wp-content\/uploads\/2014\/10\/10.16-figure1.jpg 650w, https:\/\/e-endocrinology.gr\/wp-content\/uploads\/2014\/10\/10.16-figure1-300x277.jpg 300w, https:\/\/e-endocrinology.gr\/wp-content\/uploads\/2014\/10\/10.16-figure1-624x577.jpg 624w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/><\/b><\/p>\n<p style=\"text-align: justify;\"><em><b>\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 1. <\/b><\/em>\u03a3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7 \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd TSH \u03ba\u03b1\u03b9 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd. \u03a0\u03b7\u03b3\u03ae: Wiersinga W (71).<\/p>\n<hr style=\"width: 100%; border-width: 1px; border-style: solid; border-color: #CCCCCC; color: #ffffff;\" noshade=\"noshade\" width=\"100%\" \/>\n<h5 style=\"text-align: justify;\"><b>4.1. \u0395\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c3\u03b5 \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc<\/b><\/h5>\n<p style=\"text-align: justify;\">\u0389\u03b4\u03b7 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03ad\u03bd\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03c0\u03bf\u03c5 \u03ba\u03c5\u03bc\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc 1-5% \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03a5\u03a0\u0398 \u03b8\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03b5\u03b9 \u03c3\u03c4\u03bf \u03bc\u03ad\u03bb\u03bb\u03bf\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03ad\u03ba\u03b4\u03b7\u03bb\u03b7 \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7. \u03a4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b1\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 \u03ae \u03b1\u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03cc\u03c1\u03b9\u03c3\u03c4\u03b7 \u03c4\u03b9\u03bc\u03ae TSH, \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5 \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf\u03c5\u03c2 \u03b1\u03c5\u03c4\u03cc\u03bd\u03bf\u03bc\u03bf\u03c5\u03c2 \u00ab\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03bf\u03cd\u03c2\u00bb \u03cc\u03b6\u03bf\u03c5\u03c2 (5,30). \u0397 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03b1\u03c5\u03c4\u03ae \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b5\u03ba\u03b4\u03b7\u03bb\u03ce\u03c3\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd.<\/p>\n<h5 style=\"text-align: justify;\"><b>4.2. \u03a3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd \u03ba\u03b1\u03b9 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b6\u03c9\u03ae\u03c2 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03a5\u03a0\u0398<\/b><\/h5>\n<p style=\"text-align: justify;\">\u03a3\u03b5 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u03bc\u03b5 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ad\u03c2 \u03bf\u03c1\u03bc\u03cc\u03bd\u03b5\u03c2, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03bf\u03c5\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7\u03c2. \u0391\u03c5\u03c4\u03cc \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u0394\u0398\u039a. \u0395\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03bd\u03b1 \u03b5\u03c0\u03b9\u03bb\u03ad\u03b3\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u0394\u0398\u039a \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bf\u03c0\u03bf\u03af\u03bf\u03c5\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03bf\u03c1\u03b7\u03b3\u03b7\u03b8\u03b5\u03af \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03cc\u03c1\u03b9\u03b1 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u03c4\u03b7\u03c2 TSH \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b5\u03bb\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac (8,37).<\/p>\n<p style=\"text-align: justify;\">\u03a3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae \u03a5\u03a0\u0398, \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1-\u03c3\u03b7\u03bc\u03b5\u03af\u03b1 \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03cc\u03c4\u03b1\u03bd \u03b1\u03ba\u03cc\u03bc\u03b1 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd, \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c0\u03b9\u03bf \u03ae\u03c0\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b1\u03c0\u03cc \u03cc\u03c4\u03b9 \u03c3\u03c4\u03bf\u03bd \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc. \u03a3\u03b5 \u03bd\u03b5\u03ce\u03c4\u03b5\u03c1\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c3\u03c5\u03c7\u03bd\u03ac \u03b1\u03bd\u03b5\u03c5\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03bd\u03b4\u03b5\u03b9\u03ba\u03c4\u03b9\u03ba\u03ac \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b1\u03b4\u03c1\u03b5\u03bd\u03b5\u03c1\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03c4\u03b1\u03c7\u03c5\u03ba\u03b1\u03c1\u03b4\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03af\u03c3\u03b8\u03b7\u03bc\u03b1 \u03c0\u03b1\u03bb\u03bc\u03ce\u03bd. \u03a3\u03b5 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ad\u03c2 \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03a5\u03a0\u0398 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03b7\u03c3\u03b7\u03c2, \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03b9\u03b4\u03b9\u03bf\u03c3\u03c5\u03b3\u03ba\u03c1\u03b1\u03c3\u03af\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03b1\u03c4\u03cc\u03bc\u03bf\u03c5 (1).<\/p>\n<h5 style=\"text-align: justify;\"><b>4.3. \u0395\u03c0\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03c5\u03ba\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03cc \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc<\/b><\/h5>\n<p style=\"text-align: justify;\">\u039f \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc \u03cc\u03c4\u03b9 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b1\u03c7\u03b5\u03af\u03b1 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03b4\u03cc\u03bc\u03b7\u03c3\u03b7, \u03c0\u03bf\u03c5 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03b9\u03c3\u03bf\u03b6\u03cd\u03b3\u03b9\u03bf \u03b1\u03c3\u03b2\u03b5\u03c3\u03c4\u03af\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03ac\u03b6\u03b1\u03c2 (38,39).<\/p>\n<p style=\"text-align: justify;\">\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03bf\u03c3\u03c4\u03b5\u03bf\u03c0\u03cc\u03c1\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03c4\u03ac\u03b3\u03bc\u03b1\u03c4\u03b1 (40,41). \u03a9\u03c3\u03c4\u03cc\u03c3\u03bf \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03b1\u03b2\u03ad\u03b2\u03b1\u03b9\u03bf\u03c2 \u03bf \u03c1\u03cc\u03bb\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03a5\u03a0\u0398 \u03c3\u03c4\u03bf\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03cc \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03c4\u03ac\u03b3\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03c3\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b9\u03ba\u03c1\u03ad\u03c2, \u03ba\u03b1\u03b9 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b1\u03ba\u03c1\u03cc\u03c0\u03bd\u03bf\u03b5\u03c2 \u03b4\u03b9\u03c0\u03bb\u03ad\u03c2 \u03c4\u03c5\u03c6\u03bb\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bc\u03b5 \u03bc\u03ac\u03c1\u03c4\u03c5\u03c1\u03b5\u03c2 (20,42-52). \u039f\u03b9 \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03a5\u03a0\u0398 \u03b4\u03b5 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c4\u03c1\u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1\u03c2. \u0394\u03cd\u03bf \u03cc\u03bc\u03c9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b1\u03bd\u03b1\u03bb\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03a5\u03a0\u0398 \u03ba\u03b1\u03c4\u03ad\u03bb\u03b7\u03be\u03b1\u03bd \u03c3\u03c4\u03bf \u03c3\u03c5\u03bc\u03c0\u03ad\u03c1\u03b1\u03c3\u03bc\u03b1 \u03cc\u03c4\u03b9 \u03bf \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1\u03c2 (43,51).<\/p>\n<p style=\"text-align: justify;\">\u0388\u03bd\u03b1 \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03bf \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03b5\u03cd\u03b8\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ae\u03bd \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd 1250 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03b1\u03c0\u03cc 41 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03c6\u03ac\u03bd\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u03bc\u03b5 \u03b8\u03c5\u03c1\u03bf\u03be\u03af\u03bd\u03b7 \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03bd \u03bc\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03c3\u03c4\u03b7\u03bd \u03bf\u03c3\u03c6\u03c5\u03ca\u03ba\u03ae \u03bc\u03bf\u03af\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b9\u03c3\u03c7\u03af\u03bf (51).<\/p>\n<p style=\"text-align: justify;\">\u03a0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b1 \u03c3\u03c7\u03b5\u03b4\u03cc\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03bd\u03b5\u03ce\u03c4\u03b5\u03c1\u03c9\u03bd \u03bc\u03b5\u03bb\u03b5\u03c4\u03ce\u03bd \u03cc\u03c0\u03bf\u03c5 \u03c6\u03ac\u03bd\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03c4\u03cc\u03c3\u03bf \u03bf \u03b5\u03be\u03c9\u03b3\u03b5\u03bd\u03ae\u03c2 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03bf \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae\u03c2 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03c5\u03ba\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03bc\u03ac\u03bb\u03b9\u03c3\u03c4\u03b1 \u03c3\u03c4\u03b9\u03c2 \u03c0\u03bb\u03bf\u03cd\u03c3\u03b9\u03b5\u03c2 \u03c3\u03b5 \u03c6\u03bb\u03bf\u03b9\u03ce\u03b4\u03b5\u03c2 \u03bf\u03c3\u03c4\u03bf\u03cd\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03ba\u03b5\u03bb\u03b5\u03c4\u03bf\u03cd, \u03b5\u03bd\u03ce \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b9\u03ba\u03c1\u03ae \u03ad\u03c9\u03c2 \u03b1\u03c3\u03ae\u03bc\u03b1\u03bd\u03c4\u03b7 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b9\u03c2 \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 (24,53-55).<\/p>\n<p style=\"text-align: justify;\">\u03a4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03be\u03c9\u03b3\u03b5\u03bd\u03bf\u03cd\u03c2 \u03ae \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03bf\u03cd\u03c2 \u03a5\u03a0\u0398 \u03c3\u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03c4\u03b1\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03b1\u03c6\u03ae \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b1\u03bc\u03c6\u03b9\u03bb\u03b5\u03b3\u03cc\u03bc\u03b5\u03bd\u03b1. \u03a3\u03b5 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c3\u03b5 686 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03ac\u03bd\u03c9 \u03c4\u03c9\u03bd 65 \u03c7\u03c1\u03cc\u03bd\u03c9\u03bd, \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b3\u03b9\u03b1 4 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1, \u03b7 \u03a5\u03a0\u0398 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03bd \u03bc\u03b5 4\u03c0\u03bb\u03ac\u03c3\u03b9\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03c3\u03c0\u03bf\u03bd\u03b4\u03c5\u03bb\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03c4\u03b1\u03b3\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 3\u03c0\u03bb\u03ac\u03c3\u03b9\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03c4\u03b1\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b9\u03c3\u03c7\u03af\u03bf\u03c5 (54).<\/p>\n<p style=\"text-align: justify;\">\u0391\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03b1\u03bb\u03bb\u03ac \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03ad\u03c3\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 60,3 \u03c7\u03c1\u03cc\u03bd\u03c9\u03bd \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03cc\u03c0\u03bf\u03c5 \u03b7 \u03b5\u03be\u03c9\u03b3\u03b5\u03bd\u03ae\u03c2 \u03a5\u03a0\u0398 \u03c3\u03c7\u03b5\u03c4\u03b9\u03b6\u03bf\u03bd\u03c4\u03b1\u03bd \u03bc\u03b5 \u03b4\u03b9\u03c0\u03bb\u03ac\u03c3\u03b9\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03bf\u03c3\u03c4\u03b5\u03bf\u03c0\u03bf\u03c1\u03c9\u03c4\u03b9\u03ba\u03bf\u03cd \u03ba\u03b1\u03c4\u03ac\u03b3\u03bc\u03b1\u03c4\u03bf\u03c2 (56). \u039f\u03b9 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b5\u03af\u03c7\u03b1\u03bd \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 \u03c4\u03b9\u03bc\u03ae TSH (&lt; 0,03 mU\/L). \u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bc\u03b5\u03c1\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 TSH (0,04 &#8211; 0,4 mU\/L) \u03b4\u03b5\u03bd \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03b6\u03b1\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03c4\u03b1\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd (54). \u03a3\u03c4\u03b9\u03c2 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b4\u03cd\u03bf \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 (54,56) \u03b4\u03b5\u03bd \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03b7\u03c2 FT4\/T3. \u03a3\u03b5 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b7 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 T4 \u03c3\u03c4\u03b7\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03c5\u03ba\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03bd \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b7\u03bc\u03b5\u03c1\u03ae\u03c3\u03b9\u03b1 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 (&gt; 1,6 \u03bcg) (57). \u03a3\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03bc\u03ac\u03bb\u03b9\u03c3\u03c4\u03b1 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03b1, \u03c0\u03c1\u03bf\u03bb\u03ac\u03bc\u03b2\u03b1\u03bd\u03b5 \u03c4\u03b7\u03bd \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 T4 \u03c3\u03c4\u03b7\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03bc\u03ac\u03b6\u03b1 (57). \u03a0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b1 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c9\u03c2 \u03b1\u03c3\u03ba\u03b5\u03af \u03ba\u03b1\u03b9 \u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03b1\u03c3\u03b2\u03b5\u03c3\u03c4\u03af\u03bf\u03c5 (58). \u0395\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03cc\u03c0\u03bf\u03c5 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b8\u03c5\u03c1\u03bf\u03be\u03af\u03bd\u03b7\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03ac\u03b6\u03b1\u03c2 \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03a5\u03a0\u0398, \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03bd \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c4\u03b9\u03bc\u03ce\u03bd \u03c4\u03b7\u03c2 TSH \u03c0\u03bf\u03c5 \u03ae\u03c4\u03b1\u03bd \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 LT4 (59). \u03a3\u03c4\u03b7\u03bd \u03b3\u03bd\u03c9\u03c3\u03c4\u03ae \u03ba\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 TEARS (Thyroid Epidemiology Additional and Research Study), \u03c0\u03b1\u03c1\u03cc\u03c4\u03b9 \u03b4\u03b9\u03b1\u03c0\u03b9\u03c3\u03c4\u03ce\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03ac\u03bd\u03c9 \u03c4\u03c9\u03bd 65 \u03c7\u03c1\u03cc\u03bd\u03c9\u03bd \u03bc\u03b5 \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc, \u03b5\u03af\u03c7\u03b1\u03bd \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03c4\u03b1\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b9\u03c3\u03c7\u03af\u03bf\u03c5 \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03bc\u03ac\u03c1\u03c4\u03c5\u03c1\u03b5\u03c2, \u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03b1\u03c5\u03c4\u03cc\u03c2 \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03b4\u03b5\u03bd \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03bd \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03c4\u03b9\u03bc\u03ad\u03c2 \u03c4\u03b7\u03c2 TSH (24). \u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03a5\u03a0\u0398 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b4\u03b5\u03af\u03ba\u03c4\u03b5\u03c2 \u03b5\u03ba\u03c4\u03af\u03bc\u03b7\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03bf\u03c3\u03c4\u03b9\u03ba\u03bf\u03cd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03bf\u03cd, \u03cc\u03c0\u03c9\u03c2 \u03b3\u03b9\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03b5\u03b9\u03b3\u03bc\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c0\u03ad\u03ba\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c3\u03c4\u03b1 \u03bf\u03cd\u03c1\u03b1 \u03c4\u03c9\u03bd \u03c0\u03c1\u03bf\u03b5\u03c1\u03c7\u03cc\u03bc\u03b5\u03bd\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf \u03ba\u03bf\u03bb\u03bb\u03b1\u03b3\u03cc\u03bd\u03bf \u03c4\u03c9\u03bd \u03bf\u03c3\u03c4\u03ce\u03bd \u03b4\u03b5\u03c3\u03bc\u03ce\u03bd \u03c0\u03c5\u03c1\u03b9\u03b4\u03bf\u03bb\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c5\u03b4\u03c1\u03bf\u03be\u03c5\u03c0\u03c1\u03bf\u03bb\u03af\u03bd\u03b7\u03c2 (60,61), \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03c3\u03c4\u03bf\u03bd \u03bf\u03c1\u03cc \u03c4\u03c9\u03bd \u03b4\u03b5\u03b9\u03ba\u03c4\u03ce\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c0\u03bf\u03c1\u03c1\u03cc\u03c6\u03b7\u03c3\u03b7\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03ba\u03b1\u03c1\u03b2\u03bf\u03be\u03c5\u03c4\u03b5\u03bb\u03b9\u03ba\u03cc-1-\u03c4\u03b5\u03bb\u03bf\u03c0\u03b5\u03c0\u03c4\u03af\u03b4\u03b9\u03bf (62). \u0393\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03bb\u03ac\u03bc\u03b2\u03b1\u03bd\u03b1\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u03bc\u03b5 LT4 \u03b3\u03b9\u03b1 \u0394\u0398\u039a, \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03b6\u03b1\u03bd \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b1\u03bc\u03b9\u03bd\u03bf-\u03c4\u03b5\u03bb\u03b9\u03ba\u03bf-\u03c4\u03b5\u03bb\u03bf\u03c0\u03b5\u03c0\u03c4\u03b9\u03b4\u03af\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03c4\u03cd\u03c0\u03bf\u03c5 1 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03bb\u03b1\u03b3\u03cc\u03bd\u03bf\u03c5 \u03c3\u03c4\u03b1 \u03bf\u03cd\u03c1\u03b1 \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03bf\u03c3\u03c4\u03b5\u03bf\u03ba\u03b1\u03bb\u03c3\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c1\u03b2\u03bf\u03be\u03c5-\u03c4\u03b5\u03bb\u03b9\u03ba\u03bf-\u03c4\u03b5\u03bb\u03bf\u03c0\u03b5\u03c0\u03c4\u03af\u03b4\u03b9\u03bf\u03c5 \u03c3\u03c4\u03bf\u03bd \u03bf\u03c1\u03cc \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03bc\u03ac\u03c1\u03c4\u03c5\u03c1\u03b5\u03c2 \u03cc\u03c7\u03b9 \u03cc\u03bc\u03c9\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03c2 \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 (63).<\/p>\n<p style=\"text-align: justify;\">\u03a3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b1\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c4\u03c9\u03bd \u03cc\u03c3\u03c9\u03bd \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b8\u03b7\u03ba\u03b1\u03bd, \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03a5\u03a0\u0398 (\u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae\u03c2 \u03ae \u03b5\u03be\u03c9\u03b3\u03b5\u03bd\u03ae\u03c2) \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03ac\u03b6\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03c4\u03b1\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b1\u03bb\u03bb\u03ac \u03bc\u03cc\u03bd\u03bf \u03c3\u03c4\u03b1 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03ac\u03c4\u03bf\u03bc\u03b1<\/p>\n<h5 style=\"text-align: justify;\"><b>4.4. \u0395\u03c0\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03b8\u03bd\u03b7\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1<\/b><\/h5>\n<p style=\"text-align: justify;\">\u039f\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc-\u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7, \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03cc\u03c4\u03b1\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b1\u03ba\u03c1\u03ac\u03c2 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2, \u03b2\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03ba\u03b1\u03b9 \u03b8\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c1\u03b9\u03bc\u03bd\u03b1 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03c4\u03b9\u03bc\u03ce\u03bd \u03c4\u03b7\u03c2 TSH \u03c3\u03c4\u03bf \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc.<\/p>\n<h4 style=\"text-align: justify;\"><b>5. \u03a0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7<\/b><\/h4>\n<p style=\"text-align: justify;\">\u038c\u03c0\u03c9\u03c2 \u03ae\u03b4\u03b7 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b8\u03b7\u03ba\u03b5, \u03c4\u03cc\u03c3\u03bf \u03b7 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03c5\u03ba\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03bf \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae\u03c2 \u03bc\u03b1\u03c1\u03bc\u03b1\u03c1\u03c5\u03b3\u03ae\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7 \u03c3\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03bd\u03bf\u03c3\u03b7\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1. \u039f\u03b9 \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b5\u03c2 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b5\u03be\u03c9\u03b3\u03b5\u03bd\u03ae \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03bb\u03b7\u03c6\u03b8\u03bf\u03cd\u03bd \u03ae \u03bd\u03b1 \u03b4\u03b9\u03bf\u03c1\u03b8\u03c9\u03b8\u03bf\u03cd\u03bd \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03c4\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c4\u03b9\u03c4\u03bb\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03bc\u03b5 LT4 \u03bc\u03b5 \u03c3\u03c4\u03cc\u03c7\u03bf \u03bd\u03b1 \u03b4\u03b9\u03b1\u03c4\u03b7\u03c1\u03b7\u03b8\u03bf\u03cd\u03bd \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03b7\u03c2 TSH \u03b5\u03bd\u03c4\u03cc\u03c2 \u03c4\u03c9\u03bd \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03af\u03c9\u03bd. \u03a3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03c4\u03b7\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03bc\u03b5 LT4 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ae \u03bc\u03b5 \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b7\u03b8\u03ad\u03bd \u0394\u039a\u0398 \u03b7 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 TSH \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03cc\u03c7\u03b5\u03c5\u03c3\u03b7. \u039a\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03b1\u03c5\u03c4\u03ae\u03bd \u03ba\u03b1\u03b9 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03ae \u03b7\u03bb\u03b9\u03ba\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2, \u03ae \u03c0\u03bf\u03c5 \u03b2\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03b5\u03c1\u03af\u03bf\u03b4\u03bf \u03cd\u03c6\u03b5\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03bc\u03b1\u03ba\u03c1\u03cc \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03b4\u03b9\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03bf\u03cd\u03bd \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c4\u03b7\u03c2 TSH \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 \u03c4\u03b7\u03c2 LT4 (9).<\/p>\n<p style=\"text-align: justify;\">\u0391\u03bd\u03b1\u03c6\u03bf\u03c1\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 LT4 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bf\u03b6\u03ce\u03b4\u03b7 \u03ae \u03c0\u03bf\u03bb\u03c5\u03bf\u03b6\u03ce\u03b4\u03b7 \u03b2\u03c1\u03bf\u03b3\u03c7\u03bf\u03ba\u03ae\u03bb\u03b7, \u03bf\u03b9 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03c3\u03b5\u03c2 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u03b4\u03b5\u03bd \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03ae \u03c4\u03b7\u03c2 (64) \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03b7 \u03c3\u03bc\u03af\u03ba\u03c1\u03c5\u03bd\u03c3\u03b7 \u03c4\u03bf\u03c5\/ \u03c4\u03c9\u03bd \u03cc\u03b6\u03c9\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bc\u03c6\u03b9\u03bb\u03b5\u03b3\u03cc\u03bc\u03b5\u03bd\u03b1 (65).<\/p>\n<p style=\"text-align: justify;\">\u03a4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 (\u03b1\u03bd\u03c4\u03b9\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u2013 RAI ) \u03c3\u03c4\u03bf\u03bd \u03b5\u03bd\u03b4\u03bf\u03b3\u03b5\u03bd\u03ae \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc, \u03c0\u03b1\u03c1\u03cc\u03c4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03b4\u03b5\u03af\u03c7\u03bd\u03bf\u03c5\u03bd \u03b5\u03c5\u03bd\u03bf\u03b9\u03ba\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03bf\u03c3\u03c4\u03b9\u03ba\u03ae \u03c0\u03c5\u03ba\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 (42,66) \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03ba\u03ac\u03c0\u03bf\u03b9\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03c4\u03c1\u03bf\u03c5\u03c2 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 (67,68). \u03a3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b5\u03c2 \u03ba\u03b1\u03c4\u03b5\u03c5\u03b8\u03c5\u03bd\u03c4\u03ae\u03c1\u03b9\u03b5\u03c2 \u03bf\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u03c4\u03b7\u03c2 ATA (American Thyroid Association) \u03ba\u03b1\u03b9 AACE (American Association of Cinical Endocronologists) \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bc\u03cc\u03bd\u03b9\u03bc\u03b1 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 TSH (&lt;0,1 mU\/L) \u03c0\u03c1\u03bf\u03c4\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03c3\u03c4\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1 &gt;65 \u03b5\u03c4\u03ce\u03bd, \u03c3\u03c4\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03b1 \u03ae \u03b4\u03b9\u03c6\u03c9\u03c3\u03c6\u03bf\u03bd\u03b9\u03ba\u03ac, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03ac\u03c4\u03bf\u03bc\u03b1 \u03c5\u03c8\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03b5\u03ba\u03b4\u03ae\u03bb\u03c9\u03c3\u03b7 \u03bf\u03c3\u03c4\u03b5\u03bf\u03c0\u03cc\u03c1\u03c9\u03c3\u03b7\u03c2 \u03ae \u03bc\u03b5 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 (69). \u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1 \u03b4\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bf\u03bc\u03bf\u03c6\u03c9\u03bd\u03af\u03b1 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b7 \u03b1\u03b3\u03c9\u03b3\u03ae \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c4\u03b9\u03bc\u03ad\u03c2 TSH &lt;0,1 mU\/L \u03c7\u03c9\u03c1\u03af\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5, \u03bf\u03cd\u03c4\u03b5 \u03c3\u03b5 \u03cc\u03c3\u03bf\u03c5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03b7 \u03c4\u03b9\u03bc\u03ae TSH (0,1-0,6 mU\/L). \u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03bf \u03b5\u03af\u03b4\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7\u03c2 \u03b1\u03c5\u03c4\u03cc \u03b5\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03b9\u03c4\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03bf\u03cd \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd, \u03cc\u03c0\u03c9\u03c2 \u03b9\u03c3\u03c7\u03cd\u03b5\u03b9 \u03ac\u03bb\u03bb\u03c9\u03c3\u03c4\u03b5 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ad\u03ba\u03b4\u03b7\u03bb\u03bf\u03c5 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03bf\u03cd (<b>\u03a0\u03af\u03bd\u03b1\u03ba\u03b1\u03c2 2<\/b>).<\/p>\n<p style=\"text-align: justify;\"><b>\u03a0\u03af\u03bd\u03b1\u03ba\u03b1\u03c2 2. <\/b>\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7\u03c2 \u03c3\u03c4\u03bf\u03bd \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc [\u039c\u03b5\u03c4\u03b1\u03c6\u03c1\u03b1\u03c3\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc Ross DS (10)].<\/p>\n<table style=\"width: 100%;\" border=\"0\" cellspacing=\"3\" cellpadding=\"3\" align=\"left\">\n<tbody>\n<tr style=\"background-color: #385a72;\">\n<td width=\"180\"><b>\u00a0<\/b><\/td>\n<td width=\"156\"><span style=\"color: #ffffff;\"><b>TSH<\/b><b> &lt; 0,1 <\/b><b>mU<\/b><b>\/<\/b><b>L<\/b><\/span><b><\/b><\/td>\n<td width=\"156\">&gt;<span style=\"color: #ffffff;\"><b>TSH<\/b><b> 0,1 &#8211; 0,4 <\/b><b>mU<\/b><b>\/<\/b><b>L<\/b><\/span><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"180\">\u0391\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2<\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"180\"><b>\u03a3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03af<\/b><\/td>\n<td valign=\"top\" width=\"156\">\u0388\u03bd\u03b4\u03b5\u03b9\u03be\u03b7<\/td>\n<td valign=\"top\" width=\"156\">\u03a0\u03b9\u03b8\u03b1\u03bd\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"180\"><b>\u03a5\u03c8\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/b><\/td>\n<td valign=\"top\" width=\"156\">\u0388\u03bd\u03b4\u03b5\u03b9\u03be\u03b7<\/td>\n<td valign=\"top\" width=\"156\">\u03a0\u03b9\u03b8\u03b1\u03bd\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"180\">\u039c\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2<\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"180\">\u039f\u03c3\u03c4\u03b5\u03bf\u03c0\u03cc\u03c1\u03c9\u03c3\u03b7<\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"180\">\u039a\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf\u03c2<\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"180\">\u0397\u03bb\u03b9\u03ba\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf\u03b9 (&gt; 65 \u03b5\u03c4\u03ce\u03bd)<\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"180\"><b>\u03a7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5<\/b><\/td>\n<td valign=\"top\" width=\"156\">\u03a0\u03b9\u03b8\u03b1\u03bd\u03ae \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7<\/td>\n<td valign=\"top\" width=\"156\">\u0391\u03c0\u03bf\u03c5\u03c3\u03af\u03b1 \u03ad\u03bd\u03b4\u03b5\u03b9\u03be\u03b7\u03c2<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"180\">\u039c\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2<\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"180\">\u0391\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 (&lt; 65 \u03b5\u03c4\u03ce\u03bd) \u03c7\u03c9\u03c1\u03af\u03c2 \u03c3\u03c5\u03bd\u03bf\u03b4\u03ac \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1<\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<td valign=\"top\" width=\"156\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4 style=\"text-align: justify;\"><\/h4>\n<h4 style=\"text-align: justify;\">\u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1<\/h4>\n<p style=\"text-align: left;\">1. 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B; 2001. p. 1491-506.<\/p>\n<hr style=\"width: 100%; border-width: 1px; border-style: solid; border-color: #CCCCCC; color: #ffffff;\" noshade=\"noshade\" width=\"100%\" \/>\n<p style=\"text-align: justify;\">Created: October 26, 2014<br \/>\nLast update: October 26, 2014<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u039d\u03b9\u03ba\u03cc\u03bb\u03b1\u03bf\u03c2 \u03a0\u03bf\u03bd\u03c4\u03b9\u03ba\u03af\u03b4\u03b7\u03c2, \u039c\u03b1\u03c1\u03af\u03b1 \u039a\u03b1\u03c1\u03b1\u03bc\u03c0\u03b1\u03c4\u03ac\u03ba\u03b7, \u03a3\u03c0\u03c5\u03c1\u03af\u03b4\u03c9\u03bd \u039a\u03b1\u03c1\u03c1\u03ac\u03c2 K\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u0395\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 &#8211; \u03a3\u03b1\u03ba\u03c7\u03b1\u03c1\u03ce\u03b4\u03b7 \u0394\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7 \u03ba\u03b1\u03b9 \u039c\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03bf\u03cd \u0393.\u039d. \u0386\u03b3\u03b9\u03bf\u03c2 \u03a0\u03b1\u03cd\u03bb\u03bf\u03c2 \u2018\u03a0\u03b1\u03c1\u03ac\u03c1\u03c4\u03b7\u03bc\u03b1 \u03a0\u03b1\u03bd\u03b1\u03b3\u03af\u03b1\u2019, \u0398\u03b5\u03c3\u03c3\u03b1\u03bb\u03bf\u03bd\u03af\u03ba\u03b7 &nbsp; \u0395\u03b9\u03c3\u03b1\u03b3\u03c9\u03b3\u03ae \u039f \u03cc\u03c1\u03bf\u03c2 \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 (\u03a5\u0398\u0394) \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03c0\u03bf\u03bb\u03cd \u03c0\u03c1\u03ce\u03b9\u03bc\u03bf \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf (\u03b2\u03b9\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03cc, \u03c0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03ae \u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc) \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2 (\u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c5\u03c0\u03bf\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u2013\u03a5\u03a5\u0398) \u03ae \u03c4\u03b7\u03c2 \u03c0\u03b5\u03c1\u03af\u03c3\u03c3\u03b5\u03b9\u03b1\u03c2 \u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd (\u03c5\u03c0\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b8\u03c5\u03c1\u03b5\u03bf\u03b5\u03b9\u03b4\u03b9\u03c3\u03bc\u03cc\u03c2 \u03ae \u03b8\u03c5\u03c1\u03b5\u03bf\u03c4\u03bf\u03be\u03af\u03ba\u03c9\u03c3\u03b7-\u03a5\u03a0\u0398). \u0397 \u03a5\u0398\u0394 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"pageCustom.php","meta":{"footnotes":""},"tags":[],"_links":{"self":[{"href":"https:\/\/e-endocrinology.gr\/index.php?rest_route=\/wp\/v2\/pages\/777"}],"collection":[{"href":"https:\/\/e-endocrinology.gr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/e-endocrinology.gr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/e-endocrinology.gr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/e-endocrinology.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=777"}],"version-history":[{"count":11,"href":"https:\/\/e-endocrinology.gr\/index.php?rest_route=\/wp\/v2\/pages\/777\/revisions"}],"predecessor-version":[{"id":780,"href":"https:\/\/e-endocrinology.gr\/index.php?rest_route=\/wp\/v2\/pages\/777\/revisions\/780"}],"wp:attachment":[{"href":"https:\/\/e-endocrinology.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=777"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/e-endocrinology.gr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}